摘要：Objective To observe the clinical effects and safety on female depression treated with the combined therapy of acupuncture and the five-element music therapy. Methods A total of 120 female patients with depression were randomized into an electroacupuncture (EA) group, an acupuncture group, a five-element music therapy group and a group of tlie combined therapy of acupuncture and the five-element music therapy (combined therapy group), 30 cases in each one. In the EA group, the electric stimulation of acupuncture was applied at Baihui (GV20),Shenting ( GV24), Neiguan (PC6), Shenmen (HT7), Sanyinjiao (SP6) and Taic hong (LR 3), with disperse-dense wave, 10 Hz/50 Hz, and 0.5 ms in wave length.